Family Identifier |
NMF333 |
Synonym(s) |
A.B6 Tyr+-nmf333/J; JR#5445 |
Synopsis |
The mutants show head tilt and occasional head tossing behavior.
|
Gene Symbol |
nmf333 (View MGI Record) |
Gene |
neuroscience mutagenesis facility333 |
Allele Symbol |
nmf333 (View MGI Record) |
Allele |
neuroscience mutagenesis facility333 |
Abnormal Assay(s) |
Assay: Overt movement/posture
Domain(s): Auditory/Vestibular
; Visible Mutants
|
Phenotype Description |
These mutants were detected through routine inspections for overt abnormal behavior; head- and body tilt can be observed at approximately 4 weeks of age (average onset 4.6 +/- 0.6 weeks; n=15). Male or female mutants have been produced and the colony is maintained through regular breeding.
(View video)
|
Pathology Report |
Standard pathology work-up and a whole-mount ear exam on one mutant (56 days of age) revealed no abnormalities. |
HERITABILITY AND MAPPING INFORMATION
|
Background Strain |
A.B6 Tyr+ |
Heritability Mode |
Recessive |
Heritability Status |
Proven; 3 different heterozygous x heterozygous matings produced 15 mutants in a total of 50 progeny.
|
Chromosome |
8 |
Molecular Interval |
D8Mit248 - 5 cM (LOD 4.0) - D8Mit213 - 10 cM (LOD 3.2) - [D8Mit13, NMF333] 0 cM (LOD 6.0) |
Map
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STATUS INFORMATION
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Mutant Status |
Cryopreserved Embryos
|
Comments |
(22) NMF333/DNA have been requested by and distributed to 3 investigators. |
Contact e-Mail Address |
nmf-mice@jax.org |