Family Identifier |
NMF282 |
Synonym(s) |
JR#6026; A.B6 Tyr+-nmf282/J |
Synopsis |
Retinal spots. |
Gene Symbol |
nmf282 (View MGI Record) |
Gene |
neuroscience mutagenesis facility282 |
Allele Symbol |
nmf282 (View MGI Record) |
Allele |
neuroscience mutagenesis facility282 |
Abnormal Assay(s) |
Assay: Indirect ophthalmoscopy
Domain(s): Eye/Vision
|
Phenotype Description |
Routine ophthalmoscopic examination at 12 weeks of age revealed retinal spots in mutant eyes. Male or female mutants have been identified and the colony is maintained through heterozygote matings.
|
Pathology Report |
Standard pathology work-up on two mutants (214 or 443 days of age) revealed severe retinal degeneration; vacuolation of the brain was also noted in the older mouse. |
HERITABILITY AND MAPPING INFORMATION
|
Background Strain |
A.B6-Tyr+ |
Heritability Mode |
Recessive |
Heritability Status |
Proven; 1 het x het mating resulted in 3 mutants in a total of 14 progeny. |
STATUS INFORMATION
|
Mutant Status |
Cryopreserved Embryos
|
Comments |
Please note: While this mutation is available, it has not yet been chromosomally mapped - an important part of determining whether it is allelic with a previously characterized mutation. |
Contact e-Mail Address |
nmf-mice@jax.org |