Family Identifier |
NMF268 |
Synonym(s) |
C56BL/6J-nmf268/J;JR#5101 |
Synopsis |
White retinal spots. |
Gene Symbol |
nmf268 (View MGI Record) |
Gene |
neuroscience mutagenesis facility268 |
Allele Symbol |
nmf268 (View MGI Record) |
Allele |
neuroscience mutagenesis facility268 |
Abnormal Assay(s) |
Assay: Indirect ophthalmoscopy
Domain(s): Eye/Vision
|
Phenotype Description |
Routine ophthalmoscopic examination at 11 weeks of age showed white spots on mutant retinae. NMF268 mutants breed well and a colony can be maintained through heterozygote or homozygote matings.
|
Pathology Report |
Standard pathology work-up on one mutant (211 days of age) revealed no abnormalities. Additional pathology is in progress.
|
HERITABILITY AND MAPPING INFORMATION
|
Background Strain |
C57BL/6J |
Heritability Mode |
Recessive |
Heritability Status |
Proven; 1 heterozygote x heterozygote mating resulted in 4 mutants in a total of 14 progeny; 1 homozygote x homozygote mating resulted in 5 mutants in a total of 6 progeny. |
STATUS INFORMATION
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Mutant Status |
Cryopreserved Embryos
|
Comments |
Please note: While this mutation is available, it has not yet been chromosomally mapped - an important part of determining whether it is allelic with a previously characterized mutation. (6) NMF268 have been requested by and distributed to 2 investigator. |
Contact e-Mail Address |
nmf-mice@jax.org |