MUTANT MOUSE LINES AVAILABLE NOW

Click on one of the domain names below to view mutant lines which are presently available in that domain. Some mutants may be listed under multiple domains.

Auditory/Vestibular (19)
NMF4Visible head tilt; slight body tremor.
NMF9Head nodding detectable at weaning age.
NMF19 Circling behavior by weaning age, deaf by 14 weeks of age; reduced grip strength.
NMF110The mutants are small and have an unsteady gait; they are also deaf.
NMF112Circling behavior, slight head tilt; mutants are deaf.
NMF118Small with body tremor; mutants are hearing impaired.
NMF172Circling (bi-directional), head tossing behavior observed by weaning age; the mutants are deaf.
NMF181Circling, head tossing behavior; the mutants are deaf.
NMF190Circling, head tilt and head tossing behavior; the mutants are deaf.
NMF219Circling and head tossing behavior observed by weaning age; mutants are deaf.
NMF250The mutants show head and body tilt at 4 weeks of age.
NMF252Circling behavior, head tilt and tossing observed by weaning age; the mutants are deaf.
NMF318The mutants are deaf, show circling and head tossing behavior.
NMF329The mutants are deaf.
NMF333The mutants show head tilt and occasional head tossing behavior.
NMF370Mutants show bi-directional circling behavior.
NMF371Circling (bi-directional), head tilt and head tossing behavior; the mutants are deaf.
NMF430Deaf with head and body tilt, circling behavior.
NMF455Body tremor, head tossing and bi-directional circling behavior.
Epilepsy (6)
NMF31Heterozygotes have high threshold to electroconvulsive minimal clonic seizures.
NMF63Intermittent movement disorder.
NMF88Low threshold to electroconvulsive minimal clonic seizures.
NMF134Low threshold to electroconvulsive minimal clonic seizures.
NMF350Low threshold to electroconvulsive minimal clonic seizures.
SZT1Heterozygotes have low threshold for electroconvulsive and PTZ-induced seizures; homozygotes show perinatal lethality.
Eye/Vision (17)
NMF11Impaired gait, mutants are small; abnormal ERG.
NMF12Thin retina; white intraretinal patches.
NMF67Splayed, weak hind limbs, body tremor; the mutants are small and have retinal defects.
NMF128The mutants show spots on retina and in vitreous body.
NMF131Hyaloid remnants and vitreal fibroplasia with white retinal spots.
NMF137Mottled retina, white retinal vessels.
NMF144Retinal spots; the phenotype represents a Crb1rd8like mutation, however the expression is milder in NMF144 than that observed in Crb1rd8mutants.
NMF166Lens extrusion cataract and deep anterior chamber.
NMF191Grainy retina.
NMF192Retinal spots, mottled retinae.
NMF193Mottled retina indicative of pan retinal photoreceptor degeneration.
NMF195Grainy retina.
NMF240Mottled retina and atrophied retinal blood vessels.
NMF246Grainy retina, retinal spots.
NMF247Retinal spots, vitreal fibroplasia.
NMF268White retinal spots.
NMF282Retinal spots.
Growth/Development (12)
NMF2Early onset bilateral hind limb paralysis; the mutants are small.
NMF5 Early onset bilateral hind limb paralysis; the mutants are small, have a thin retina.
NMF11Impaired gait, mutants are small; abnormal ERG.
NMF58 Seal-like gait; the mutants are small with severely impaired gait.
NMF65Low grip strength and hind limb weakness.
NMF67Splayed, weak hind limbs, body tremor; the mutants are small and have retinal defects.
NMF110The mutants are small and have an unsteady gait; they are also deaf.
NMF111The mutants are small and show a subtle body tremor; thinning of peripheral retina.
NMF118Small with body tremor; mutants are hearing impaired.
NMF127The mutants are small and ataxic.
NMF148Small, body tremor, severely impaired gait.
NMF203Mutants are small and show abnormal gait with splayed hind limbs.
Gustation/Olfaction (1)
NMF253Mutants are polydipsic.
Histology (4)
NMF5 Early onset bilateral hind limb paralysis; the mutants are small, have a thin retina.
NMF67Splayed, weak hind limbs, body tremor; the mutants are small and have retinal defects.
NMF111The mutants are small and show a subtle body tremor; thinning of peripheral retina.
NMF243The mutants are ataxic.
Movement/Neuromuscular Function (57)
NMF2Early onset bilateral hind limb paralysis; the mutants are small.
NMF4Visible head tilt; slight body tremor.
NMF5 Early onset bilateral hind limb paralysis; the mutants are small, have a thin retina.
NMF11Impaired gait, mutants are small; abnormal ERG.
NMF19 Circling behavior by weaning age, deaf by 14 weeks of age; reduced grip strength.
NMF58 Seal-like gait; the mutants are small with severely impaired gait.
NMF62Low grip strength and abnormal gait.
NMF63Intermittent movement disorder.
NMF65Low grip strength and hind limb weakness.
NMF67Splayed, weak hind limbs, body tremor; the mutants are small and have retinal defects.
NMF110The mutants are small and have an unsteady gait; they are also deaf.
NMF111The mutants are small and show a subtle body tremor; thinning of peripheral retina.
NMF118Small with body tremor; mutants are hearing impaired.
NMF127The mutants are small and ataxic.
NMF148Small, body tremor, severely impaired gait.
NMF161Intermittent hind- and front limb spasms.
NMF164The mutants exhibit an intense body tremor and unsteady gait.
NMF203Mutants are small and show abnormal gait with splayed hind limbs.
NMF205The mutants show an unsteady gait, weak hind limbs.
NMF206The mutants develop a body tremor by weaning age.
NMF220Intense body tremor (at rest and during movement) observed by weaning age.
NMF242Splayed hind limbs, unsteady gait, torso swaying.
NMF243The mutants are ataxic.
NMF244The mutants show ‘hot-foot’ like behavior and a dilute brown coat.
NMF249The mutants are small and develop an unsteady gait.
NMF261The mutants have weak hind limbs, body tremor.
NMF267The mutants are small, with splayed hind limbs, and unable to walk continuously upright.
NMF291Splayed hind limbs, staggering gait.
NMF293Body tremor, unstable gait.
NMF299Small, splayed hind limbs, body tremor and intermittent body spasms.
NMF310Intermittent loss of hind limb function (myotonia).
NMF313The mutants show splayed hind limbs, body tremor and staggering gait.
NMF334Body tremor, trunk swaying, high lifting of hind limbs.
NMF335Hind and front limb movement impaired, head tossing.
NMF339Severely impaired front- and hind limb function.
NMF347Body tremor, head nodding.
NMF352The mutants are small, weak hind limbs, and intermittent loss of hind limb function.
NMF355Intermittent hind limb spasms.
NMF356Hind limb spasms, body tremor.
NMF369Splayed hind limbs, body tremor, torso swaying of progressive severity.
NMF373The mutants show intense body tremor and trunk swaying at rest and during movement.
NMF375Weak hind limbs, intermittent hind limb spasms.
NMF379Intense body tremor at rest and during movement, hind limb spasms.
NMF380Small, weak hind limbs, body tremor.
NMF391Small, with front and hind limb spasms.
NMF403Splayed, weak hind limbs, front limbs turned medially.
NMF408Body tremor, ataxic.
NMF413Body tremor, intense hind limb spasms, unable to walk continuously without falling over.
NMF417Muscular dystrophy and hypomyelination.
NMF418Intermittent hind limb spasms of progressive severity.
NMF419Weak hind limbs, body tremor.
NMF420Side leaning and head nodding of progressive severity; tendency to move backward.
NMF422Body tremor, splayed hind limbs, side leaning.
NMF430Deaf with head and body tilt, circling behavior.
NMF455Body tremor, head tossing and bi-directional circling behavior.
NMF470Intense body tremor during movement, head nodding.
NMF474Abnormal hind limb function.
Visible Mutants (69)
NMF2Early onset bilateral hind limb paralysis; the mutants are small.
NMF4Visible head tilt; slight body tremor.
NMF5 Early onset bilateral hind limb paralysis; the mutants are small, have a thin retina.
NMF9Head nodding detectable at weaning age.
NMF11Impaired gait, mutants are small; abnormal ERG.
NMF19 Circling behavior by weaning age, deaf by 14 weeks of age; reduced grip strength.
NMF58 Seal-like gait; the mutants are small with severely impaired gait.
NMF62Low grip strength and abnormal gait.
NMF63Intermittent movement disorder.
NMF65Low grip strength and hind limb weakness.
NMF67Splayed, weak hind limbs, body tremor; the mutants are small and have retinal defects.
NMF110The mutants are small and have an unsteady gait; they are also deaf.
NMF111The mutants are small and show a subtle body tremor; thinning of peripheral retina.
NMF112Circling behavior, slight head tilt; mutants are deaf.
NMF118Small with body tremor; mutants are hearing impaired.
NMF127The mutants are small and ataxic.
NMF148Small, body tremor, severely impaired gait.
NMF161Intermittent hind- and front limb spasms.
NMF164The mutants exhibit an intense body tremor and unsteady gait.
NMF172Circling (bi-directional), head tossing behavior observed by weaning age; the mutants are deaf.
NMF181Circling, head tossing behavior; the mutants are deaf.
NMF190Circling, head tilt and head tossing behavior; the mutants are deaf.
NMF203Mutants are small and show abnormal gait with splayed hind limbs.
NMF205The mutants show an unsteady gait, weak hind limbs.
NMF206The mutants develop a body tremor by weaning age.
NMF219Circling and head tossing behavior observed by weaning age; mutants are deaf.
NMF220Intense body tremor (at rest and during movement) observed by weaning age.
NMF242Splayed hind limbs, unsteady gait, torso swaying.
NMF243The mutants are ataxic.
NMF244The mutants show ‘hot-foot’ like behavior and a dilute brown coat.
NMF249The mutants are small and develop an unsteady gait.
NMF250The mutants show head and body tilt at 4 weeks of age.
NMF252Circling behavior, head tilt and tossing observed by weaning age; the mutants are deaf.
NMF261The mutants have weak hind limbs, body tremor.
NMF267The mutants are small, with splayed hind limbs, and unable to walk continuously upright.
NMF291Splayed hind limbs, staggering gait.
NMF293Body tremor, unstable gait.
NMF299Small, splayed hind limbs, body tremor and intermittent body spasms.
NMF310Intermittent loss of hind limb function (myotonia).
NMF313The mutants show splayed hind limbs, body tremor and staggering gait.
NMF318The mutants are deaf, show circling and head tossing behavior.
NMF333The mutants show head tilt and occasional head tossing behavior.
NMF334Body tremor, trunk swaying, high lifting of hind limbs.
NMF335Hind and front limb movement impaired, head tossing.
NMF339Severely impaired front- and hind limb function.
NMF347Body tremor, head nodding.
NMF352The mutants are small, weak hind limbs, and intermittent loss of hind limb function.
NMF355Intermittent hind limb spasms.
NMF356Hind limb spasms, body tremor.
NMF369Splayed hind limbs, body tremor, torso swaying of progressive severity.
NMF370Mutants show bi-directional circling behavior.
NMF371Circling (bi-directional), head tilt and head tossing behavior; the mutants are deaf.
NMF373The mutants show intense body tremor and trunk swaying at rest and during movement.
NMF375Weak hind limbs, intermittent hind limb spasms.
NMF379Intense body tremor at rest and during movement, hind limb spasms.
NMF380Small, weak hind limbs, body tremor.
NMF391Small, with front and hind limb spasms.
NMF403Splayed, weak hind limbs, front limbs turned medially.
NMF408Body tremor, ataxic.
NMF413Body tremor, intense hind limb spasms, unable to walk continuously without falling over.
NMF417Muscular dystrophy and hypomyelination.
NMF418Intermittent hind limb spasms of progressive severity.
NMF419Weak hind limbs, body tremor.
NMF420Side leaning and head nodding of progressive severity; tendency to move backward.
NMF422Body tremor, splayed hind limbs, side leaning.
NMF430Deaf with head and body tilt, circling behavior.
NMF455Body tremor, head tossing and bi-directional circling behavior.
NMF470Intense body tremor during movement, head nodding.
NMF474Abnormal hind limb function.